Pregnancy Loss Pregnancy Loss Causes and Risk Factors When Most Miscarriages Happen By Krissi Danielsson Krissi Danielsson Krissi Danielsson, MD is a doctor of family medicine and an advocate for those who have experienced miscarriage. Learn about our editorial process Updated on April 20, 2020 Medically reviewed by Meredith Shur, MD Medically reviewed by Meredith Shur, MD Meredith Shur, MD, FACOG, is board-certified in obstetrics and gynecology, as well as a certified medical examiner. Learn about our Medical Review Board Print Tim Hale/Stone/Getty Images Table of Contents View All Table of Contents What Is a Miscarriage? How Common Are Miscarriages? Causes Pregnancy is obviously a time of anxiety as well as anticipation, and a lot of pregnant women worry, especially those who have had a miscarriage before. Some seek comfort in statistics, feeling a greater sense of relief after passing specific milestones in pregnancy at which statistical odds of miscarriage decrease. You may want to know at what point in pregnancy will you be able to breathe a sigh of relief and stop worrying so much about having a miscarriage. What Is a Miscarriage? An early pregnancy loss is a pregnancy loss or miscarriage before the 13th week of gestation (during the first trimester). Pregnancy losses that occur between 13 and 19 weeks gestation are called second-trimester pregnancy losses or second-trimester miscarriages. A pregnancy loss at 20 weeks or greater gestation is not called a miscarriage, but a stillbirth—where the fetus dies in the mother's uterus. According to the American College of Obstetricians and Gynecologists, approximately 80 percent of miscarriages happen within the first trimester. As pregnancy progresses, miscarriage risk decreases. In addition, your risk of miscarriage drops significantly after a doctor detects a heartbeat on an ultrasound. How Common Are Miscarriages? If you're wondering when miscarriages occur, you may also have questions about how common miscarriages are. The good news is that by the time you actually get a positive pregnancy test, your risk of miscarriage will be at the lower end of that range. In an older study in the New England Journal of Medicine, researchers followed 221 women over a combined total of 707 menstrual cycles, with 198 total pregnancies. They found that 22 percent of the pregnancies ended before they could be detected clinically (such as by standard urine pregnancy tests). Including the early miscarriages, the total miscarriage rate was 31 percent. Current evidence backs up this older study, suggesting that anywhere between 8 and 20 percent of recognized pregnancies will end in miscarriage and 30 to 40 percent of all conceptions end in miscarriage. While early pregnancy loss occurs in about 10 percent of all recognized pregnancies, second-trimester miscarriages occur in about 1 to 5 percent of pregnancies. Stillbirth occurs in about 0.3 percent of pregnancies. Causes About half of miscarriages are caused by chromosomal abnormalities, making these problems the single most common miscarriage cause. Most of these are random one-time occurrences that are not inherited from the parents. The earlier in pregnancy a miscarriage occurs, the more likely it was caused by a chromosomal abnormality. The miscarriage rate after 15 weeks for fetuses that are free of chromosomal or structural abnormalities is only about 0.6 percent. Usually, these abnormalities are aneuploidies, meaning there is an incorrect number of chromosomes, either an extra chromosome (as in the case of trisomy 21 or Down syndrome) or a missing chromosome. The biggest miscarriage risk factor is a mother's age. According to the American College of Obstetrics and Gynecologists, the number of miscarriages in the first trimester for women increases dramatically as a woman ages. Here are the statistics showing this rise: Age 20 to 30 years: 9 to 17% miscarriage rateAge 35 years: 20% miscarriage rateAge 40 years: 40% miscarriage rateAge 45 years: 80% miscarriage rate The miscarriage rate is lower for women who have had a child previously, about 5 percent up to 20 gestational weeks. A Word From Verywell If you have experienced a miscarriage in the past, are worried you may have one, or both, please know that you are not alone. If your worry is persistent and affecting how you feel and function, be sure to seek guidance from your doctor. There are a number of therapies available that can help you feel better. Stages of Grief Following a Miscarriage Sources Verywell Family uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. The American College of Obstetricians and Gynecologists. Practice Bulletin: Early Pregnancy Loss. Number 150, May 2015. Reaffirmed 2017. Tulandi T, Al-Fozan HM. Spontaneous Abortion: Risk Factors, Etiology, Clinical Manifestations, and Diagnostic Evaluation. In: UpToDate, Levine D, Barbieri RL (Ed), UpToDate, Waltham, MA. Tulandi T. Patient education: Miscarriage (Beyond the Basics). In: UpToDate, Barbieri RL (Ed), UpToDate, Waltham, MA. Wilcox et al. Incidence of early loss of pregnancy. N Engl J Med. 1988 Jul 28;319(4):189-94. By Krissi Danielsson Krissi Danielsson, MD is a doctor of family medicine and an advocate for those who have experienced miscarriage. See Our Editorial Process Meet Our Review Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? Other Helpful Report an Error Submit