Getting Vaccines in Pregnancy

Influenza vaccine

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When seemingly harmless things like cold cuts and soft-serve ice cream suddenly become off-limits, the world can be a downright scary place for someone who is pregnant. The many do's and don'ts can leave you feeling cautious about everything you put in your body—including getting vaccinated. But like prenatal vitamins and exercise, vaccines are an important part of a healthy pregnancy.

Recommended Vaccines

Two vaccines are recommended during each and every pregnancy: the flu shot and Tdap. Both are important to maintain not only the health of the parent during and after pregnancy, but also to protect the health of the baby in the womb and during those first few months of life.

The Flu Shot

Between 12,000 to 61,000 people in the United States die from the flu every year—more than all other vaccine-preventable diseases combined—and pregnant people are especially at risk. Because of the way the human body changes during those critical 40 weeks, pregnancy leaves you more vulnerable to infection from viruses like the flu, and if you do fall ill, you're more likely to be hospitalized or die as a result.

While there are several ways you can protect yourself from getting sick while pregnant—such as frequent hand-washing and healthy eating—the single best way to protect yourself from flu is by getting vaccinated. The best time to receive the flu shot is in early fall before the flu season is in full swing, regardless of where you are in your pregnancy.

Getting the flu shot during pregnancy also protects newborns. Infants don't receive their first dose of the flu vaccine until they are at least 6 months old. Until that time, they are vulnerable to a severe infection. Babies whose moms were vaccinated during pregnancy, however, are significantly less likely to be hospitalized as a result of flu during the first six months of life.

Protecting yourself during pregnancy lowers the chances you'll pass the virus onto your baby, but your baby also receives passive immunity from you while in the womb, which will help them fight off the virus if they are exposed during their first few months.

Tdap Vaccine

The same is true for the Tdap—or tetanus, diphtheria, and acellular pertussis—vaccine. While pertussis in adults is often very mild, pertussis (whooping cough) in infants can be devastating. Babies don't get their first dose of pertussis vaccine until two months old, but those first eight weeks are a vulnerable time for newborns, especially if they become infected with pertussis.

About half of all infants under one year with pertussis are hospitalized, and about 20 die each year as a result of the infection—most are under 3 months old. Pregnant people who get the Tdap vaccine during the third trimester pass on protective antibodies to their babies in the womb and those antibodies help to protect newborns until they can begin the pertussis vaccination series themselves.

Other Vaccines

Other vaccines might also be recommended if you intend to travel outside of the United States during your pregnancy, or if you have certain risk factors. People with chronic liver conditions might be encouraged to get the hepatitis A vaccine, for example, while those planning to travel to certain parts of Africa might need to be vaccinated against meningococcal disease.

Not all travel vaccines have been shown to be safe during pregnancy, however. So it's important to talk to your healthcare provider or visit a travel clinic before receiving vaccines.

Is the COVID-19 Vaccine Safe?

When it comes to the COVID-19 vaccine, the Centers for Disease Control and Prevention (CDC) advises people who are pregnant to get vaccinated, due to the fact that the risk of severe illness from COVID-19 is increased in pregnancy.

That said, the decision to be vaccinated should be made in cooperation with your provider.

Vaccine Safety

No vaccine—or any medical product—is 100% safe. But side effects from vaccination are almost always mild and temporary, and severe effects like a strong allergic reaction are rare.

The important question asked by those who make the vaccination schedule is whether the benefit of vaccination outweighs any known risks. And given the severe risks associated with diseases like flu and pertussis, research has made a strong case for maternal vaccination.

While studies on the COVID-19 vaccine in pregnant people are limited, data from both human and animal research has not revealed any pregnancy-related safety concerns related to the Moderna, Pfizer-BioNTech, or J&J/Janssen vaccines.

What the Research Says

A 2017 study in the journal Vaccine made headlines when researchers found a possible link between the flu vaccine and miscarriage, sparking some concern among pregnant people about whether they should be vaccinated against the flu.

While this is understandably alarming, the CDC was quick to point out that pregnant women should still be vaccinated against the flu, and that both prior and subsequent research showed no increased risk for miscarriage after a flu vaccine. The 2017 study didn't determine that the vaccine caused miscarriages, only that women who miscarried were more likely to have received the flu vaccine in the 2010-2011 and 2011-2012 flu seasons.

The safety of the Tdap vaccine during pregnancy has also been well documented, and studies show it to be safe and effective at protecting mom and baby from pertussis. Like the flu vaccine, the most common side effects are arm soreness, fatigue, and fever. Severe allergic reactions to the vaccine are extraordinarily rare, especially in adults.

Both the flu shot and the Tdap vaccine can be given safely at the same time or at separate visits, and it doesn't matter how recently you received a tetanus shot. 

Some online forums and websites have posted misleading or inaccurate information about the ingredients in vaccines, leading some moms to worry about their safety. Specifically, they often single out thimerosal, which is an ethylmercury-containing compound sometimes used to keep vaccines safe from contamination.

Very few vaccines use this component, and studies researching its effect show no evidence of harm and no increase in the baby's risk for autism. If you would still prefer to avoid thimerosal, however, there are thimerosal-free versions of the flu vaccine available, and it is not used in the creation of the Tdap vaccine.

Vaccines to Avoid

While vaccines can be beneficial, some should be avoided—if possible—during pregnancy. Vaccines that use live but weakened viruses, for example, such as the MMR or chickenpox vaccines, carry a theoretical risk to the baby and therefore shouldn't be given to pregnant people.

If you get vaccinated with one of these vaccines before you learn you're pregnant, don't panic. The recommendation to avoid them is largely just a precaution. Studies looking at women who were inadvertently vaccinated with live vaccines during pregnancy didn't find any evidence of harm to the babies.

Even though you shouldn't be vaccinated against these diseases during pregnancy, you could still become infected and experience severe complications as a result. If you're planning to get pregnant—but aren't pregnant yet—be sure to talk to your healthcare provider about what vaccines you should get beforehand so that you're protected throughout your pregnancy. This is especially important for the rubella vaccine, as a rubella infection during pregnancy can cause birth defects and miscarriage.

Vaccines for Friends and Family 

Expecting parent aren't the only ones who should get vaccinated. Other caregivers, siblings, grandparents, and anyone else who will be interacting with the baby during the first few months of life should also be fully up-to-date on all vaccines—including the annual flu shot. If possible, visitors should get their vaccines at least two weeks before meeting the baby so that they have time to develop sufficient immunity.

Asking loved ones to get vaccinated can be awkward, especially if they have expressed hesitancy toward vaccination in the past. Resources are available from parent-led advocacy groups like Voices for Vaccines to help guide you through the conversation if you experience or anticipate pushback.

While the prospect of confrontation can be daunting, it's an important step to keep your baby as safe as possible, as many diseases—including flu and measles—can be spread even if symptoms are mild or absent. Not all vaccines are 100% effective, which is why everyone who can be vaccinated safely should be vaccinated.

A Word From Verywell

Getting vaccinated during pregnancy is an important way to protect your health and the health of your growing baby. If you have any questions or concerns about vaccine side effects or risks during pregnancy, talk to your healthcare provider.

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Article Sources
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  1. Centers for Disease Control and Prevention. Disease burden of influenza. Updated June 11, 2021.

  2. Centers for Disease Control and Prevention. Flu and pregnant women. Updated April 12, 2021.

  3. Benowitz I, Esposito DB, Gracey KD, Shapiro ED, Vázquez M. Influenza vaccine given to pregnant women reduces hospitalization due to influenza in their infants. Clin Infect Dis. 2010;51(12):1355-1361. doi:10.1086/657309

  4. Centers for Disease Control and Prevention. Whooping cough is deadly for babies. Updated June 29, 2017.

  5. Centers for Disease Control and Prevention. Get the whooping cough vaccine during each pregnancy. Updated June 10, 2021.

  6. Centers for Disease Control and Prevention. COVID-19 vaccines while pregnant or breastfeeding. Updated June 29, 2021.

  7. Donahue JG, Kieke BA, King JP, et al. Association of spontaneous abortion with receipt of inactivated influenza vaccine containing H1N1pdm09 in 2010–11 and 2011–12. Vaccine. 2017;35(40):5314-5322. doi:10.1016/j.vaccine.2017.06.069

  8. Centers for Disease Control and Prevention. Addressing concerns pregnant women might have about influenza vaccine safety. Updated October 22, 2019.

  9. Centers for Disease Control and Prevention. Pregnancy and whooping cough: Research. Updated June 29, 2017.

  10. Centers for Disease Control and Prevention. Whooping cough vaccines are safe but side effects can occur. Updated June 29, 2017.

  11. U.S. Food and Drug Administration. Thimerosal in vaccines questions and answers. Updated February 2, 2018.

  12. Price CS, Thompson WW, Goodson B, et al. Prenatal and infant exposure to thimerosal from vaccines and immunoglobulins and risk of autism. Pediatrics. 2010;126(4):656-664. doi:10.1542/peds.2010-0309

  13. World Health Organization. Safety of immunization during pregnancy: A review of the evidence. 2014.

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