Fertility Challenges Treatment Beta-hCG Levels and What They Mean By Rachel Gurevich, RN Rachel Gurevich, RN Facebook LinkedIn Twitter Rachel Gurevich is a fertility advocate, author, and recipient of The Hope Award for Achievement, from Resolve: The National Infertility Association. She is a professional member of the Association of Health Care Journalists and has been writing about women’s health since 2001. Rachel uses her own experiences with infertility to write compassionate, practical, and supportive articles. Learn about our editorial process Updated on October 15, 2021 Medically reviewed Verywell Family articles are reviewed by board-certified physicians and family healthcare professionals. Medical Reviewers confirm the content is thorough and accurate, reflecting the latest evidence-based research. Content is reviewed before publication and upon substantial updates. Learn more. by Brian Levine, MD, MS, FACOG Medically reviewed by Brian Levine, MD, MS, FACOG Brian Levine, MD, MS, is board-certified in obstetrics and gynecology as well as in reproductive endocrinology and infertility. Learn about our Medical Review Board Print Verywell / Photo Illustration by Michela Buttignol / Getty Images Many pregnant women and those trying to conceive may have heard the term beta-hCG in relation to pregnancy testing and wonder what it means. Beta-hCG (β-hCG) is a test that measures the amount of human chorionic gonadotropin (hCG) in the blood. This hormone is produced as soon as 10 days post-conception and an above-normal level can confirm pregnancy. Aside from this, the beta-hCG test may also be used during evaluations of fertility treatments (a synthetic form of the hormone is sometimes used to help follicles mature and trigger ovulation), as well as when there are concerns that something may be wrong with a pregnancy. Also Known As The beta-hCG blood test is also sometimes called the:Quantitative blood pregnancy testQuantitative hCG blood testQuantitative serial beta-hCG testQuantitative serum beta-HCG test What Beta hCG Measures Pregnancy testing involves the detection of hCG either in the urine or blood. The urine test is a qualitative one in that it can only tell you if the sample is positive or negative for hCG. The same goes for the qualitative hCG blood test. In contrast, the beta hCG is a quantitative test, meaning it reveals not just that the hormone is present in the blood, but in exactly what amounts. Levels of hCG are measured in milli-international units per milliliter (mIU/ml). When Beta-hCG Tests Are Used The beta-hCG test may be done to confirm pregnancy at an early prenatal doctor's visit (as a follow-up to a positive at-home or in-office urine test). But the beta hCG is not always done or necessary in routine pregnancies. Many practitioners use transvaginal ultrasound at pregnancy confirmation visits to actually see visible evidence of the pregnancy (the gestational sac) instead. The beta-hCG test is also used when there are concerns about pregnancy complications, including miscarriage. In these situations, repeat tests may be performed every two to three days to evaluate how quickly hCG levels are rising. Early on in pregnancy, the rate of increase is more telling than the actual quantity of the hormone in the blood. Slow-to-rise hCG levels may indicate a high risk for miscarriage. If you are undergoing fertility treatments, your doctor may order a beta-hCG test just before or when your period is due to see if the efforts were successful. Doctors caring for women taking hCG shots to improve their chances of conception or as part of the intrauterine insemination (IUI) or in vitro fertilization (IVF) process need to carefully time a beta-hCG test to ensure that the medication has cleared the body and will not affect test results. Other uses for the beta-hCG test during pregnancy include: Determining the age of a fetus: A beta-hCG test cannot always pinpoint the precise gestational age. However, your results—considered alongside the date of your last period—can give your doctor a general idea, as expected hCG ranges change with each passing week in the first trimester.Fetal screening: A beta hCG is one part of both the maternal serum triple and quadruple screening tests done between 15 and 20 weeks' gestation to assess for markers of certain fetal health problems, including Down syndrome. Unrelated to pregnancy, the beta-hCG test may help diagnose some cancers. Beta hCG Levels in Pregnancy The following are the typical ranges of hCG levels during pregnancy. These ranges are just guidelines, as every pregnancy is different. Expected hCG Levels in the First Trimester Time Since Last Period hCG Range (if Pregnant) 3 Weeks 5 to 72 mIU/ml 4 Weeks 10 to 708 mIU/ml 5 Weeks 217 to 8,245 mIU/ml 6 Weeks 152 to 32,177 mIU/ml 7 Weeks 4,059 to 153,767 mIU/ml 8 Weeks 31,366 to 149,094 mIU/ml 9 Weeks 59,109 to 135,901 mIU/ml 10 Weeks 44,186 to 170,409 mIU/ml 12 Weeks 27,107 to 201,165 mIU/ml 14 Weeks 24,302 to 93,646 mIU/ml 16 Weeks 8,904 to 55,332 mIU/ml Remember: Whether you have high or low levels of the hormone is not the key indicator of a healthy pregnancy. This is because many factors can influence total hCG levels, including maternal smoking, weight, ethnicity, parity (the number of times a woman has given birth), and hyperemesis gravidarum (severe morning sickness). Doctors instead look to see if hCG levels double every 48 to 72 hours from whatever level they started at. They look for this in the initial weeks of pregnancy, as it's normal for hCG levels to peak around 8 to 11 weeks' gestation, then decrease, and level off thereafter. What Are hCG Doubling Times? If Beta-hCG Levels Are Lower Than Expected If your hCG levels are low, it is likely that another test will be performed in a few days to confirm if levels are increasing or not. If your beta-hCG levels are lower than expected (and remain low in repeated testing), this may indicate: Miscalculated gestational age Possible miscarriage Ectopic pregnancy (when a fertilized egg implants outside of the uterus) If one of these issues is suspected, your practitioner will do other tests, typically a transvaginal ultrasound, to determine the status of your pregnancy. What Do Low hCG Levels Mean? If Beta-hCG Levels Are Higher Than Expected Reasons your beta-hCG levels may be higher than expected include: A multiple pregnancy Incorrect pregnancy date Molar pregnancy (when a mass of tissue grows inside of the uterus instead of a placenta) Again, an atypical result will be followed up with repeat testing and/or other evaluations to figure out what is going on. What Do High hCG Levels Mean? A Word From Verywell If you see your hCG results on a lab report before you have the opportunity to speak about them with your doctor, try not to jump to your own conclusions. While informative, a beta-hCG test is just one way that doctors gather information about—and determine the status of—a pregnancy. Was this page helpful? Thanks for your feedback! Get diet and wellness tips to help your kids stay healthy and happy. Sign Up You're in! Thank you, {{form.email}}, for signing up. There was an error. Please try again. What are your concerns? Other Inaccurate Hard to Understand Submit 6 Sources Verywell Family uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Mount Sinai. HCG blood test-quantitative. Nwabuobi C, Arlier S, Schatz F, Guzeloglu-Kayisli O, Lockwood CJ, Kayisli UA. hCG: Biological functions and clinical applications. Int J Mol Sci. 2017;18(10):2037. doi:10.3390/ijms18102037 Korevaar TI, Steegers EA, de Rijke YB, et al. Reference ranges and determinants of total hCG levels during pregnancy: the Generation R Study. Eur J Epidemiol. 2015;30(9):1057-1066. doi:10.1007/s10654-015-0039-0 C.S. Mott Children's Hospital. Michigan Medicine. Human chorionic gonadotrophin (HCG). October 8, 2020. Barnhart KT, Guo W, Cary MS, et al. Differences in serum human chorionic gonadotropin gise in early pregnancy by race and value at presentation. Obstet Gynecol. 2016;128(3):504-511. doi:10.1097/AOG.0000000000001568 Matorras R, Meabe A, Mendoza R, et al. Human chorionic gonadotropin (hCG) plasma levels at oocyte retrieval and IVF outcomes. J Assist Reprod Genet. 2012;29(10):1067-1071. doi:10.1007/s10815-012-9826-7 By clicking “Accept All Cookies”, you agree to the storing of cookies on your device to enhance site navigation, analyze site usage, and assist in our marketing efforts. Cookies Settings Accept All Cookies