Everyday Wellness Symptoms Of Hand Foot Mouth Disease Question of the Week By Vincent Iannelli, MD Vincent Iannelli, MD Facebook Vincent Iannelli, MD, is a board-certified pediatrician and fellow of the American Academy of Pediatrics. Dr. Iannelli has cared for children for more than 20 years. Learn about our editorial process Updated on January 18, 2022 Medically reviewed by Sarah Rahal, MD Medically reviewed by Sarah Rahal, MD LinkedIn Sarah Rahal, MD is a double board-certified adult and pediatric neurologist and headache medicine specialist. Learn about our Medical Review Board Print Hand, Foot, & Mouth Disease. Tom Merton / Getty Images Table of Contents View All Table of Contents Symptoms of Hand, Foot, and Mouth Disease Getting an Accurate Diagnosis HFMD Look-A-Likes What To Know Symptoms of Hand, Foot, and Mouth Disease Typical symptoms of hand, foot, and mouth disease include: red spots or blisters on the palms of their hands and on their fingersred spots or blisters on the soles of their feet and on their toesulcers in a child's mouth (especially their tongue, gums, and inside of the cheeks) Other symptoms can include a fever, rash on the child's buttocks and legs, and mild pain from the mouth ulcers. Are They Hand, Foot, Mouth Disease Symptoms? While it is often easy to diagnose a child with classic symptoms of hand, foot, and mouth disease, there are other childhood infections that cause similar symptoms and not all cases of HFMD are so classic. For example, some kids with HFMD: may not have a fevermay only have mouth ulcers (herpangina) and may not have blisters on their hands and feetmay only have a few mouth ulcersmay have peeling on their fingers and toes and may even lose their fingernails and toenails a few weeks after the other symptoms have gone away And some kids don't have any symptoms at all, but may still be contagious. HFMD Look-A-Likes And other conditions can cause mouth ulcers or a rash on a child's hand's and feet. Herpes simplex virus type 1 can cause mouth ulcers and fever in children but doesn't cause hand or feet blisters. Ehrlichiosis and Rocky Mountain Spotted Fever can both cause rashes that involve a child's palms and soles, but since they are followed by a tick bite, they likely won't easily be confused with HFMD. Other rashes that involve the palms and soles, like reactive arthritis and Secondary Syphilis, are uncommon in the age group that gets HFMD and typically have a lot of other symptoms. And still other conditions cause skin peeling, like scarlet fever and Kawasaki disease. What To Know About Hand, Foot, and Mouth Disease Symptoms Other things to know about the symptoms of Hand, Foot, and Mouth Disease include that: Kids don't necessarily need to be kept out of daycare when they have HFMD unless they are drooling a lot or have a fever.HFMD is not the same thing as foot-and-mouth disease, which occurs in cattle, pigs, and sheep.Hand, Foot, and Mouth Disease is usually caused by the coxsackievirus A16 virus and goes away without treatment, although symptomatic treatments to control pain can be helpful. Important complications to look for include dehydration, especially if your child has painful mouth ulcers and is not eating and drinking well.Enterovirus 71 and coxsackievirus A6 can also cause HFMD.While most people get natural immunity to HFMD when they infected as kids, some older kids and parents can get HFMD if they aren't immune. How To Tell If Your Child Is Dehydrated Talk to your pediatrician if you think that your child has hand, foot, and mouth disease. Sources Verywell Family uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. AAP Red Book 2015. Committee on Infectious Diseases 2012–2015 Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 8th ed. By Vincent Iannelli, MD Vincent Iannelli, MD, is a board-certified pediatrician and fellow of the American Academy of Pediatrics. Dr. Iannelli has cared for children for more than 20 years. See Our Editorial Process Meet Our Review Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? Other Helpful Report an Error Submit