What Is a Corpus Luteum Cyst?

Ultrasound technicians examining pregnant woman

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A corpus luteum cyst is a type of ovarian cyst (a small, fluid-filled sac). The corpus luteum itself is a vital, but temporary temporary endocrine structure. It forms from cells in the ovarian follicle wall during ovulation. This type of cyst happens when the corpus luteum continues to grow rather than break down as it typically does.

Also called a corpus luteal cyst, this condition often occurs during pregnancy. It can also appear at other times, primarily during the reproductive years.

What Is the Corpus Luteum?

Understanding the ovulation process can help explain how and why these cysts develop.

Your ovaries have thousands of follicles, which are little pouches that hold eggs. Once a follicle releases an egg during ovulation, it forms the corpus luteum—a short-lived structure that releases estrogen and progesterone, hormones that ready the uterus for implantation.

The breakdown of the corpus luteum helps to trigger menstruation. If conception occurs, the corpus luteum sticks around longer to produce hormones. The placenta will take over the function of progesterone production at around 12 weeks gestation.

Typically, the corpus luteum will disintegrate around 11 to 12 days after ovulation if conception does not occur and at between 7 and 9 weeks during pregnancy. However, sometimes, a corpus luteum cyst can develop on the ovary instead. When this happens the corpus luteum fills with blood and keeps growing rather than breaking down at the typical time. Usually, the cyst is benign, painless, and will eventually go away on its own.


In many cases, women who have a corpus luteal cyst do not experience any pain or other symptoms. In fact, a corpus luteal cyst will typically resolve on its own after a few menstrual cycles without a woman even knowing it was there.

The most common symptom in those who do take notice of a corpus luteam cyst is a slight twinge of one-sided pain or mild tenderness during the menstrual cycle. However, if there is some pain, it can mimic the type of pain associated with an ectopic or tubal pregnancy. Consult with your doctor or midwife if you have any pain you are concerned about.

Note that you also may have a corpus luteum cyst and not be aware of it. Many people have them without knowing since they are often painless and are typically only detected if an early ultrasound is given.

When to Seek Emergency Care

Large corpus luteum cysts have the potential to burst and cause internal bleeding. They can also lead to ovarian torsion, a rare but serious complication in which the ovary twists around surrounding tissues.

Immediate medical attention is needed if any symptoms of these conditions arise, including the following:

  • Fainting or dizziness
  • Shoulder pain
  • Sudden, severe, sharp, one-sided pain in the lower abdomen or pelvis
  • Vomiting and/or nausea

Identifying Corpus Luteum Cysts

Corpus luteal cysts are typically diagnosed with a transvaginal ultrasound, also called an internal ultrasound. A transvaginal ultrasound allows for a closer view of pelvic structures than a pelvic ultrasound offers. However, these cysts may also be seen using a pelvic ultrasound, which is a non-invasive diagnostic ultrasound tool that's placed on top of the abdominal skin.

In a transvaginal ultrasound, your provider inserts a wand called a transducer into your vagina. The device emits sound waves that produce images of the inside of your body and projects them on to a monitor.

While an ultrasound (transvaginal or pelvic) may be ordered if you have symptoms, cysts are often found during a routine ultrasound for other purposes, such as pregnancy confirmation or to investigate pelvic pain or excess vaginal bleeding, in women who are pregnant and those who are not.

Corpus luteum cysts vary in size but are usually between 2 and 6 centimeters. They are usually not a cause for concern. However, these cysts can occasionally lead to complications, which are typically unrelated to pregnancy itself.

Corpus luteum cysts are considered "functional" cysts. This means they typically do not cause harm, rarely need medical intervention, and do not impact fertility.

There may be more opportunities to spot a corpus luteal cyst in a woman who's expecting, simply because they're usually having routine imaging as part of their prenatal care. For this reason, these cysts are diagnosed more often during pregnancy.

Your doctor or midwife may want you to have a follow-up ultrasound to check on the cyst if you continue to have symptoms. Otherwise, unless pain or other symptoms necessitate treatment, no follow-up is typically needed.

Risk Factors

Anyone can get corpus luteum cysts, though they are more likely to develop in women taking medication to induce ovulation, like Clomid (clomiphene). These medications, which manipulate hormones in order to stimulate ovulation, are usually prescribed by a doctor or midwife for women experiencing fertility problems and for those with polycystic ovary syndrome (PCOS).

It's important to remember that since the corpus luteum is a normal part of the menstrual cycle, the type of functional ovarian cyst associated with them can also develop when you are not pregnant. You can also develop one even if you are not taking, or have never taken, medication to treat infertility.

Additionally, the following risk factors put you at greater risk of developing a corpus luteum cyst:

  • Endometriosis
  • Hormonal imbalance (this may be related to fertility treatment)
  • Pelvic infection
  • Pregnancy
  • Prior corpus luteum cysts

Having had a corpus luteum cyst in one pregnancy does not necessarily mean you will develop one in another pregnancy. However, it is more likely. Additionally, if you have risk factors, such as a hormonal imbalance or endometriosis, then you're more likely to have a cyst again in a subsequent (or first) pregnancy. Additionally, sometimes the cause of a corpus luteum cyst is unknown.


A corpus luteum cyst is usually not harmful. The cysts do not typically cause any complications during pregnancy, especially when they're discovered during the first trimester. If the cyst continuing to grow or worsen, surgery may be required to avoid the risk of miscarriage.

If the cyst is causing pain, your doctor or midwife may prescribe pelvic rest (no sexual activity) or pain medications. However, in most cases, a corpus luteum cyst will resolve on its own without intervention.

Occasionally, the cyst will rupture. Pain may increase when this happens but tends to subside quickly. Pain medication and rest may be indicated. Less frequently, a corpus luteum cyst can cause the ovary to twist (torsion). This can be very painful and may require surgery to prevent further injury of the ovary.

Can a Corpus Luteum Cyst Be Cancerous?

No. These cysts are what are called functional cysts—sacs that form on the ovary simply due to the normal process of menstruation. Unlike some other ovarian cysts, these do not have the potential to become cancerous.

A Word From Verywell

While it may feel unsettling to learn you have an ovarian cyst, corpus luteum cysts usually do not cause pain or complicate pregnancy or birth. Also, they rarely require any treatment. 

11 Sources
Verywell Family uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
  1. Baerwald AR, Adams GP, Pierson RA. Form and function of the corpus luteum during the human menstrual cycleUltrasound Obstet Gynecol. 2005;25(5):498-507. doi:0.1002/uog.1891

  2. National Institutes of Health. Ovarian cysts: overview.

  3. Kumar P, Magon N. Hormones in pregnancyNiger Med J. 2012;53(4):179–183. doi:10.4103/0300-1652.107549

  4. Sivalingam VN, Duncan WC, Kirk E, Shephard LA, Horne AW. Diagnosis and management of ectopic pregnancyJ Fam Plann Reprod Health Care. 2011;37(4):231–240. doi:10.1136/jfprhc-2011-0073

  5. Medvediev MV, Malvasi A, Gustapane S, Tinelli A. Hemorrhagic corpus luteum: clinical management updateTurk J Obstet Gynecol. 2020;17(4):300-309. doi:10.4274/tjod.galenos.2020.40359

  6. Sayasneh A, Ekechi C, Ferrara L, et al. The characteristic ultrasound features of specific types of ovarian pathology (review)Int J Oncol. 2015;46(2):445–458. doi:10.3892/ijo.2014.2764

  7. Ross E, Fortin C. Ovarian Cysts. Cleveland Clinic.

  8. Legro RS, Brzyski RG, Diamond MP, et al. Letrozole versus clomiphene for infertility in the polycystic ovary syndromeN Engl J Med. 2014;371(2):119–129. doi:10.1056/NEJMoa1313517

  9. Lee MS, Moon MH, Woo H, Sung CK, Jeon HW, Lee TS. Ruptured corpus luteal cyst: prediction of clinical outcomes with CT. Korean J Radiol. 2017;18(4):607-614. doi:10.3348/kjr.2017.18.4.607

  10. Lee MS, Moon MH, Woo H, Sung CK, Jeon HW, Lee TS. Ruptured corpus luteal cyst: Prediction of clinical outcomes with CTKorean J Radiol. 2017;18(4):607–614. doi:10.3348/kjr.2017.18.4.607

  11. Hakoun AM, AbouAl-Shaar I, Zaza KJ, Abou-Al-Shaar H, A Salloum MN. Adnexal masses in pregnancy: An updated reviewAvicenna J Med. 2017;7(4):153–157. doi:10.4103/ajm.AJM_22_17

Additional Reading

By Robin Elise Weiss, PhD, MPH
Robin Elise Weiss, PhD, MPH is a professor, author, childbirth and postpartum educator, certified doula, and lactation counselor.