Medications to Help Ease Morning Sickness

Medication for morning sickness is usually the last resort. There are many non-medicinal things that you should try before looking at medication for morning sickness. When these fail, you should talk to your midwife or doctor about using medication for morning sickness to help you through the worst of it.

The good news is that there is help available for women with extreme sickness. In fact, there are two types of medication for morning sickness: over the counter medication and prescription medication. The one medication for you is one that you and your practitioner decide on.

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What Does Morning Sickness Feel Like?

Over-the-Counter Medications for Morning Sickness

Over the counter medications don't require a prescription. This doesn't mean that you shouldn't use the guidance of the practitioner you're seeing for your prenatal care. There isn't just one morning sickness pill you can take and have your nausea and vomiting disappear, but some of these have been helpful to some people.

  • Vitamin B6
  • Reflux medications (Pepcid, Tums)
  • Emetrol
  • Unisom Nighttime Sleep Aid (not the SleepGels) combined with vitamin B6
  • Some herbal substances, such as ginger

Even though there some products for morning sickness do not require a prescription from your healthcare provider, you should always communicate with your practitioner about your symptoms and any products that you take to relieve them.

Prescription Medications for Morning Sickness

If you are really struggling and other over the counter morning sickness pills haven't helped, your practitioner may decide that prescription medication is the best option for you.

  • Diclegis
  • Zofran (expensive, not always covered by insurance)
  • Phenergan (pill and suppository form)
  • Compazine
  • Reglan (metoclopramide)
  • Corticosteroids (dexamethasone)

There are also IV medications and other medications used to treat hyperemesis gravidarum, severe morning sickness, often requiring hospitalization.

"Without the medication, I couldn't have continued," explains one mom. "It was really a lifesaver. I was just within hours of being hospitalized."

Medications are not used for the entire pregnancy unless symptoms persist that long. You and your practitioner can talk about what the best plan is for your pregnancy.

Medications are the last line of defense for most mothers and practitioners. The first trimester, when most morning sickness occurs is a very delicate time in terms of fetal development. You want to avoid as many medical interventions as possible, while still being able to maintain your life and employment in a way that is manageable to your family.

If medication winds up being the right path for you, try not to stress about it once the decision is made. Try to relax, knowing you've done your research and hope that you get some sweet relief from the morning sickness medication.

2 Sources
Verywell Family uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
  1. Ebrahimi N, Maltepe C, Einarson A. Optimal management of nausea and vomiting of pregnancy. Int J Womens Health. 2010;2:241-8. doi:10.2147/ijwh.s6794

  2. Nuangchamnong N, Niebyl J. Doxylamine succinate-pyridoxine hydrochloride (Diclegis) for the management of nausea and vomiting in pregnancy: an overview. Int J Womens Health. 2014;6:401-9. doi:10.2147/IJWH.S46653

By Robin Elise Weiss, PhD, MPH
Robin Elise Weiss, PhD, MPH is a professor, author, childbirth and postpartum educator, certified doula, and lactation counselor.