The 7 Best Baby Wipes of 2021

Make diaper changes a breeze with these nursery must-haves

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Our Top Picks
The wipes are 20 percent thicker than regular Pampers wipes and tend to stay more moist than competitors.
Best for Sensitive Skin:
WaterWipes Original Baby Wipes at Amazon
Effectively clean even the most irritable skin without causing extra irritation thanks to the chemical-free, water-based formula
The pH-balanced aloe and Vitamin E formula work together to keep diaper rashes at bay without causing irritation
This favorite from Seventh Generation is free of dyes and perfumes, but it also packs a punch in the cleaning department.
Best for Diaper Rashes:
Mustela Baby Cleansing Wipes at Amazon
Formulated from 97 percent plant-based ingredients that help soothe irritated skin
Made from ultra-soft bamboo cloth a more sustainable material than the plant-based fabrics used in other wipes
Besides being great on the environment, these also eliminate the use of harsh chemicals.

Past diapers, wipes are are a must-have baby essential for all households. Besides ensuring your baby has a clean diaper area, they are also a must for cleaning faces, dirty hands, and even stains on the carpet.

Many babies can be sensitive to perfumes or ingredients in wipes, so you might want to start with a small package of wipes and see if they don't cause any reaction. You'll also probably want to switch out your wipes once they start eating solid foods. Newborn poop is a lot different than toddler poop and you will need a heavier-duty wipe to deal with daily messes.

Here, the best diaper wipes.

Best Overall: Pampers Sensitive Water Based Baby Diaper Wipes

  • Readily available

  • Pop top container

  • Thick and durable

  • Not environmentally friendly

  • Hard to pull out just one wipe

A bestseller in both the baby skincare and diaper wipes categories, the Pampers Sensitive Water Baby Wipes are mild, hypoallergenic, and perfume-free. Including ingredients such as water, citric acid, castor oil, benzyl alcohol, and aloe barbadensis leaf juice, the wipes are 20 percent thicker than regular Pampers wipes. They are also used in many hospitals across the United States.

Customers say that the wipes work well on children with even the most sensitive skin and that using them saves money on diaper rash cream. The Pampers Sensitive Water Baby Wipes also tend to stay moist for a long time​ which leads to you using fewer wipes during a diaper change as compared to other brands of wipes.

Best for Sensitive Skin: WaterWipes Original Baby Wipes

  • Good for sensitive and eczema prone skin

  • Can be used on face and hands

  • Dries out easily if package isn’t closed

  • Hard to remove from packaging

Made of 99.9 percent pure water with a drop of grapefruit seed extract, WaterWipes Sensitive Baby Wipes received a Seal of Acceptance™ from the National Eczema Association of America. Completely devoid of chemicals, these wipes are safe for newborns, and effectively clean even the most irritable skin.

Parents note that these are the only wipes that don’t inflame sensitive skin. Others warn that if the wipes are not kept in a cool, dark place, they are susceptible to mold, so don't buy too much at once. Also as your kid grows and starts to eat solids you might need a more substantial wipe.

Best for Newborns: Huggies Natural Care Baby Wipes

  • Readily available 

  • Relatively inexpensive

  • Unscented formulation

  • No pop top on container

  • Very wet wipes

Made of 99 percent triple-filtered water, the HUGGIES Natural Care Unscented Baby Wipes are formulated specifically for sensitive newborn skin. Free of fragrances, alcohol and parabens, the wipes are pH-balanced and contain aloe and Vitamin E, ingredients that prevent rashes and keep a baby’s skin healthy.

The wipes are gentle enough for newborns, but also are hearty enough to use on toddlers. Parents love how strong and moist the wipes are, even when the package is left open.

Best for Toddlers: Seventh Generation Baby Wipes

  • Easy to close top

  • Thick and soft wipes

  • Good for hands, face, etc.

  • Can stick together

Once your baby starts eating solid foods, you might want to opt for a heavier wipe that can handle bigger messes. This favorite from Seventh Generation is free of dyes and perfumes, but it also packs a punch in the cleaning department.

Past cleaning diaper areas, these are great for hands, faces, and car seat messes so they are always great to have on hand. The handy closable top keeps them fresh without worrying about them drying out.

Best for Diaper Rashes: Mustela Baby Cleansing Wipes

  • Multi-use (can be used to remove makeup)

  • Lightly scented

  • Resealable container

  • Expensive

  • Lightly scented

  • Small wipe size

A definite splurge when compared to other brands, the Mustela Cleansing Wipes are great when you need to address a specific skin concern such as a diaper rash. Formulated from 97 percent plant-based ingredients such as Avocado Perseose, which protects your baby’s skin, and Aloe Vera leaf extract, which soothes irritated skin, the wipes are hypoallergenic and alcohol-free.

Parents note that they use the Mustela Cleansing Wipes for more than just diaper rashes—they also clean their babies’ faces and bodies with them. The Mustela wipes can help clear up baby acne, although this isn’t clinically proven.

Best Organic: Doctor Butler's Organic Soothing Baby Wipes

  • Made from bamboo and essential oils

  • Safe for postpartum moms

  • Biodegradable

  • Expensive

  • Hard to find

  • Not sold in bulk

Many brands of baby products claim to be organic, but very few withstand scrutiny. Doctor Butler’s Organic All Natural Chemical Free Soothing Wipes is one that lives up to the hype. Doctor Butler’s wipes are made from ultra-soft bamboo cloth, which is a more sustainable material than the plant-based fabrics used to construct most other baby wipes.

Free of chemicals and artificial preservatives, the wipes also contain organic ingredients such as Vitamin E, Rosemary Oil Extract, Lysine, Calendula Officinalis, Aloe Barbadensis Leaf Extract, and Chamomilla. Customers rave that compared to other brands advertised as organic, Doctor Butler’s wipes smell great, and work well with sensitive skin.

Best Eco-Friendly: Buttons Flannel Baby Reusable Washable Natural Unbleached Wipes

  • Washable

  • Reusable

  • Environmentally responsible

  • Requires washing after each use

  • 15 wipes per package

Although they are necessary for cleanliness, most wipes are made of tree-based fabric, which is a significant drain on natural resources. For those worried about the environment, there are wipes made out of unbleached cotton flannel.

Besides being great for the environment, these also eliminate the use of harsh chemicals on your baby's' skin and also help save you money. After each use, you will have to thoroughly clean with hot water and soap to make sure you sterilize them appropriately.

Babies go through lots of wipes. For an everyday wipe that is easy to find and comes with flip top lids, the Pampers Sensitive Water Baby Wipes (view at Amazon) is a well-loved choice for many reasons. As your kid ages, the Seventh Generation Baby Wipes (view at Amazon) are helpful. Made a bit thicker, they hold up well to clean a toddler’s dirty face, hands, and bum.

What to Look for When Buying Baby Wipes

Sensitive Skin

For babies with extra sensitive skin, regular wipes may cause irritation, drying, and overall discomfort. Skip the regular wipes and opt for for a brand that is specifically formulated to address the needs of little ones with extra-sensitive skin. Usually made with hypoallergenic ingredients, these wipes are often touted as fragrance-free, alcohol-free, and tested by dermatologists. They’re appropriate for everyday use on your baby’s sensitive skin. 


There is nothing worse than cleaning your baby's bum after a poop explosion and feeling the wipe disintegrate break into pieces. While the thicker wipes may cost a few dollars more, they will actually help you save in the long run as you'll use less per diaper change thanks to their cleaning efficiency.


All wipes are not created equal. Some are formulated with just water (or 99 percent water) while others have an extra hydrating formula to help moisturize your little one's most delicate areas. Depending on your baby's needs, you'll want to take a look at the formula to make sure it includes what your baby needs.

Disposable vs Reusable

Disposable wipes are most common but some families may choose to use reusable wipes, which are more environmentally conscious. While at home, reusable wipes can be convenient, but if you’re on the road, it’s much more of a hassle to store and then wash the wipes. Plan for your lifestyle and if you choose reusable wipes, it can be helpful to have a pack or two of disposable wipes just in case.

Why Trust Verywell Family?

Brienne Walsh is a Brooklyn-based freelance writer and photographer with over seven years of experience. Her work has been featured in Art in America, Interview Magazine, The Huffington Post, Glo, New York Magazine, The New York Times, and the NY Daily News, among other publications. 

Additional reporting by Maya Polton.

Maya Polton is a former marketing manager and current freelance writer who covers food, home, and parenting. She’s also the mom of a 10-year-old son, 7-year-old son, and 3-year old daughter.

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2 Sources
Verywell Family uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
  1. Our dedication to safety. Web-Pampers-US-EN.

  2. Avocado perseose, a biomimetic patented active ingredient targeted to the needs of infants’ skin. Journal of the American Academy of Dermatology. 2014;70(5):AB143.